Showing posts with label causation. Show all posts
Showing posts with label causation. Show all posts

22 September 2019

The Impossibility of Determinism


Posted by Thomas Scarborough

Indeed, free will and determinism. It is a classic problem of metaphysics. No matter what we may think about it, we know that we have a problem. We know that things are physically determined. I line up dominos in a row, and topple the first of them with my finger. It is certain that the whole row of dominos will fall.

Are people then subject to the same kind of determinism? Are we just so many powerless humanoid shapes waiting to be knocked down by circumstances? Or perhaps, to what extent are we subject to such determinism? Is it possible for us to escape our own inner person? Our own history? Our own future? Are we even free to choose our own thoughts—much less our actions? Are we even free to believe? Each of these questions would seem to present us with a range of mightily confusing answers.

I suggest that it may be helpful to try to view the question from a broader perspective—the particular one that comes from consideration of the phenomenon of cause and effect. If I am controlled by indomitable causes, then I am not free. Yet if I am (freely) the cause of my own thoughts and actions, then I am free. Which then is it? Once we understand the dynamics of cause and effect, we should be in a better position to understand free will and determinism.

What is cause and effect?

In our everyday descriptions of our world, we say that, to paraphrase Simon Blackburn, causation is the relation between two events. It holds when, given that one event occurs, ‘it produces, or brings forth, or necessitates the second’. The burrowing aardvark caused the dam to burst; the lightning strike caused the thatch to burn; the medicine caused the patient to rally, and so on. Yet we notice in this something that is immediately problematic—which is that in order to say that there is causality, we need to have carefully defined events before and after.

But such definition is a problem. The philosopher-statesman Francis Bacon wrote of the ‘evil’ we find in defining natural and material things. ‘The definitions themselves consist of words, and those words beget others.’ Aristotle wrote that words consist of features (say, the features of a house), and those features must stand in a certain relation to one another (rubble, say, is not a house). Therefore, not only do we have words within words, but features and relations, too.

Where does it all end? It all ends nowhere. It is an endless regress. Bacon’s ‘evil’ means that our definitions dissipate into the universe. It seems much like having money in a bank, which has its money in another bank, which has its money in another bank, and so on. It is not hard to see that one will never find the money. Full definitions ultimately reach into the void.

If we want to be consistent about it, there are no events. In order to obtain events, we need to set artificial limits to our words—and artificial limits to reality itself, by excluding unwanted influences on our various constructions. But that is not the way the world really is in its totality. More than this, these unwanted influences always seem to enter the picture again somewhere along the line. This is a big part of the problem in our world today.

Of course, cause and effect quite simply work: he lit the fire; I broke the urn; they split the atom. This is good as far as it goes—yet again, such explanations work because we define before and after—and that very definition strips away a lot of what is really going on.

Where does this leave us? It leaves us without a reason to believe in cause and effect—even if we are naturally disposed to thinking that way. There is no rational framework to support it.

Someone might object. Even if we have no befores and afters, we still have a reality which is bound by the laws of the universe. There is therefore some kind of something which is not free. Yet every scientific law is about events before and after. Whatever is out there, it has nothing in common—that we can know of anyway—with such a scheme.

This may be a new way of putting it, but it is not a new idea. Albert Einstein, as an example, said that determinism is a feature of theories, rather than any aspect of the world directly. While, at the end of this post, we cannot prove free will, we can state that notions of determinism are out of the question, in the world as we know it. The world is something else, which we have not yet understood.

11 November 2018

Butter Nonsense


Posted by Martin Cohen


Last week saw President Trump throwing out a CNN reporter from the White House Press Pool for disagreeing with him about ‘the facts’.

CNN called it an attack on press freedom, but the collective response from other journalists has been muted. And no wonder, because these days the press are themselves heavily into ‘denying’ certain views. We've all heard about ‘Climate deniers’ and how evil they are, but this last month saw a vehement attack on Cholesterol deniers!

Sarah Boseley, longtime health editor of the supposedly liberal UK newspaper, The Guardian, launched the attack with a piece called:

Butter nonsense: the rise of the cholesterol deniers

The stand-first sums up the piece accurately:
‘A group of scientists has been challenging everything we know about cholesterol, saying we should eat fat and stop taking statins. This is not just bad science – it will cost lives, say experts’.
The back story is that The Guardian, has long been very chummy to the pharmaceutical industry and regularly promotes the case for expensive drugs and mocks campaigners. Its longtime medical writer, Ben Goldacre, under the heading we just saw reused by Ms Bosely of ‘bad science’, regularly wrote in favour of Big Pharma and against alternative medicine let alone common-sense approaches without ever declaring his own links. There were family links as well as a career one via the Institute of Psychiatry to many of the industries favoured by the arguments in his articles.

‘Big Phama’, firms like Unilever; SmithKline Beecham and Pfizer Limited (two producers of antidepressant drugs); Novartis Pharmaceuticals (previously Ceiba Geigy); Lilly Industries Ltd (the manufacturers of Prozac); Hoescht Marion Roussell; GlaxoSmithKline (vaccine manufacturers) … and so on smiled on his work. Goldacre even received an award for ‘science journalism’ in 2003 - the award that year being sponsored by GlaxoSmithKline.

It’s enough to make you cynical, as is the fact that in the early years of 2000, the Institute of Psychiatry held over 200 research grants with an annual value of around £14.5 million. Its second highest source of funding was the pharmaceutical industry. The Institute is part of King’s College London, and part of the UK’s public education system. Yet for all the money the public devotes to universities, and for all the special status of university academics, private money like this drives research findings.

But back to butter, and the new money-spinner today is prescribing drugs called statins in order to reduce cholesterol. Justin Smith estimated in a piece for Statin Nation that the market for these drugs was more than $19 billion and rising. In The Guardian piece, Boseley says ‘statins are out of patent and therefore no longer make money for the companies that originally put them on the market’.

Note those ‘weasel words’, ‘for the companies that originally put them on the market’.

I looked at the cholesterol debate - I could hardly NOT do - in my food book published this month *. It is (chemically speaking) a very 'complex' area (all diet things seem to be when you get into them), but there are some studies that can be talked about in a broader sense, including several iconic long-term studies of low-cholesterol diets which do seem to demonstrate:
(a) that it is effectively impossible to isolate one factor in a dietary study, (alteration of one factor disguises changes in other factors too) and

(b) in as much as it is possible, not only that there is no evidence to support the 'low cholesterol diet' approach, there are indications that it might actually increase the risk of heart disease!
The Guardian piece makes little attempt to present a 'debate' but instead pushes the view that there is an argument for refusing to give cholesterol-deniers a platform, just as some will no longer debate with climate change sceptics. The position is summed up by one of Prof Rory Collins of Oxford University, a professor of epidemiology who says quite unashamedly that by cholesterol deniers he means people who dispute the claim that diets high in cholesterol are dangerous for heart health. As Sarah Boseley puts it here, these are people saying butter is safe and statins are dangerous. BAD PEOPLE!

No real evidence is actually offered in the piece, and when I asked Ms Boseley for any background studies she might have used, she did not respond to the request.

In fact, the available evidence is very different. One small study of Australian men found swapping from butter to margarine, for example, found the death rate from heart disease went up amongst the margarine eaters. Another study, in Denmark, that put people on a low-salt diet precisely to protect heart health, found that perversely it led to cholesterol levels shooting up!

Surveying the research, some 20 years ago now, Dr Laura Corr a cardiologist at Guys Hospital in London concluded that :

‘The commonly-held belief that the best diet for prevention of coronary heart disease is a low saturated fat, low cholesterol diet is not supported by the available evidence from clinical trials"

However, seven years ago, an influential meta-analysis by the Cholesterol Treatment Trialists found that:
‘Observational studies show that there is a continuous positive relation between coronary disease risk and blood cholesterol concentrations [and] larger reductions in LDL cholesterol [the so-called 'bad cholesterol'] might well produce larger reductions in risk.’
In 2015, another systemic review by researchers from various international institutions in Japan, Sweden, UK, Ireland, US and Italy, published in the BMJ, insisted that - on the contrary! - as LDL cholesterol went down, all-cause mortality went up while higher levels of ‘bad ’ were apparently linked to living longer.

Don’t ask for new studies, as there have been so many, and yet analysis of what they prove remains completely partisan. It has been noted that the actual trial data held by the Cholesterol Treatment Trialists’ Collaboration on behalf of the industry sponsor has not been made available to other researchers, despite multiple requests over many years.

Since then, rather than demonstrate their case through persuasive research, advocates of the low-fat, low-cholesterol diets have sought to shut-down debate even trailing that new term cholesterol deniers...

After reading all the evidence, my feeling is that cholesterol levels are not simple, one dimensional values to be turned up or down like a thermostat and attempts to shoehorn it into a Manichean (good / evil) view of dietary factors risks actually harming human health. Attempts by governments and media to rule definitively on it are unwise and a distraction from practical steps that can be taken.



* ‘I Think Therefore I Eat’ is published by Turner in the U.S. on November 20

Butter Nonsense


Posted by Martin Cohen


Last week saw President Trump throwing out a CNN reporter from the White House Press Pool for disagreeing with him about ‘the facts’.

CNN called it an attack on press freedom, but the collective response from other journalists has been muted. And no wonder, because these days the press are themselves heavily into ‘denying’ certain views. We've all heard about ‘Climate deniers’ and how evil they are, but this last month saw a vehement attack on Cholesterol deniers!

Sarah Boseley, longtime health editor of the supposedly liberal UK newspaper, The Guardian, launched the attack with a piece called:

Butter nonsense: the rise of the cholesterol deniers

The stand-first sums up the piece accurately:
‘A group of scientists has been challenging everything we know about cholesterol, saying we should eat fat and stop taking statins. This is not just bad science – it will cost lives, say experts’.
The back story is that The Guardian, has often seemed to look fondly on the pharmaceutical industry and regularly promotes the case for expensive drugs and mocks campaigners. Its longtime medical writer, Ben Goldacre, under the heading we just saw reused by Ms Bosely of ‘bad science’, regularly wrote in favour of Big Pharma and against alternative medicine let alone common-sense approaches without ever declaring his own links. There were family links as well as a career one via the Institute of Psychiatry to many of the industries favoured by the arguments in his articles.

‘Big Phama’, firms like Unilever; SmithKline Beecham and Pfizer Limited (two producers of antidepressant drugs); Novartis Pharmaceuticals (previously Ceiba Geigy); Lilly Industries Ltd (the manufacturers of Prozac); Hoescht Marion Roussell; GlaxoSmithKline (vaccine manufacturers) … and so on smiled on his work. Goldacre even received an award for ‘science journalism’ in 2003 - the award that year being sponsored by GlaxoSmithKline.

It’s enough to make you cynical, as is the fact that in the early years of 2000, the Institute of Psychiatry held over 200 research grants with an annual value of around £14.5 million. Its second highest source of funding was the pharmaceutical industry. The Institute is part of King’s College London, and part of the UK’s public education system. Yet for all the money the public devotes to universities, and for all the special status of university academics, private money like this drives research findings.

But back to butter, and the new money-spinner today is prescribing drugs called statins in order to reduce cholesterol. Justin Smith estimated in a piece for Statin Nation that the market for these drugs was more than $19 billion and rising. In The Guardian piece, Ms. Boseley says ‘statins are out of patent and therefore no longer make money for the companies that originally put them on the market’.

Note those ‘weasel words’, ‘for the companies that originally put them on the market’.

I looked at the cholesterol debate - I could hardly NOT do - in my food book published this month *. It is (chemically speaking) a very 'complex' area (all diet things seem to be when you get into them), but there are some studies that can be talked about in a broader sense, including several iconic long-term studies of low-cholesterol diets which do seem to demonstrate:
(a) that it is effectively impossible to isolate one factor in a dietary study, (alteration of one factor disguises changes in other factors too) and

(b) in as much as it is possible, not only that there is no evidence to support the 'low cholesterol diet' approach, there are indications that it might actually increase the risk of heart disease!
The Guardian piece makes little attempt to present a 'debate' but instead offers the view that there is an argument for refusing to give cholesterol-deniers a platform, just as some will no longer debate with climate change sceptics. The position is summed up by one of Prof Rory Collins of Oxford University, a professor of epidemiology who says quite unashamedly that by cholesterol deniers he means people who dispute the claim that diets high in cholesterol are dangerous for heart health. As Sarah Boseley puts it here, these are people saying butter is safe and statins are dangerous. BAD PEOPLE!

No real evidence is actually offered in the piece, and when I asked Ms. Boseley for any background studies she might have used, she did not respond to the request.

In fact, the available evidence is very different. One small study of Australian men found swapping from butter to margarine, for example, found the death rate from heart disease went up amongst the margarine eaters. Another study, in Denmark, that put people on a low-salt diet precisely to protect heart health, found that perversely it led to cholesterol levels shooting up!

Surveying the research, some 20 years ago now, Dr Laura Corr a cardiologist at Guys Hospital in London concluded that :
‘The commonly-held belief that the best diet for prevention of coronary heart disease is a low saturated fat, low cholesterol diet is not supported by the available evidence from clinical trials"
However, seven years ago, an influential meta-analysis by the Cholesterol Treatment Trialists found that:
‘Observational studies show that there is a continuous positive relation between coronary disease risk and blood cholesterol concentrations [and] larger reductions in LDL cholesterol [the so-called 'bad cholesterol'] might well produce larger reductions in risk.’
In 2015, another systemic review by researchers from various international institutions in Japan, Sweden, UK, Ireland, US and Italy, published in the BMJ, insisted that - on the contrary! - as LDL cholesterol went down, all-cause mortality went up while higher levels of ‘bad ’ were apparently linked to living longer.

Don’t ask for new studies, as there have been so many, and yet analysis of what they prove remains completely partisan. It has been noted that the actual trial data held by the Cholesterol Treatment Trialists’ Collaboration on behalf of the industry sponsor has not been made available to other researchers, despite multiple requests over many years.

Since then, rather than demonstrate their case through persuasive research, advocates of the low-fat, low-cholesterol diets have sought to shut-down debate even trailing that new term cholesterol deniers...

After reading all the evidence, my feeling is that cholesterol levels are not simple, one dimensional values to be turned up or down like a thermostat and attempts to shoehorn it into a Manichean (good / evil) view of dietary factors risks actually harming human health. Attempts by governments and media to rule definitively on it are unwise and a distraction from practical steps that can be taken.

* ‘I Think Therefore I Eat’ is published by Turner in the U.S. on November 20